The RENACE-CM project, with an investment of over one million euros, studies how to slow down the accelerated ageing caused by chronic kidney disease. It is led by IMDEA Nutrition and the Autonomous University of Madrid.
According to information released by La Razón, the Madrilenian Institute for Advanced Studies (IMDEA Nutrition) and the Autonomous University of Madrid (UAM) are directing the RENACE-CM project. Its aim is to investigate therapies and nutritional strategies that slow down the ageing associated with chronic kidney disease.
The project has an investment of over one million euros and combines biomedicine, drug development, and precision nutrition. It is funded under the 2025 call for R&D health programmes from the Community of Madrid.
The project coordinator, Marta Ruiz Ortega, a professor at UAM, explains that the team will study the molecular mechanisms linking kidney damage with accelerated ageing, fibrosis, and sarcopenia, the loss of muscle mass and strength.
The consortium will integrate technologies, experimental models, and tools for designing new pharmaceutical compounds. It will combine preclinical studies with patient data and will take into account fragility and differences between men and women.
The disease, in addition to affecting the kidneys, can accelerate the ageing of the body and cause a widespread degenerative process, impacting the quality of life of patients. According to the project, the combination of nutrition and new drugs will help prevent complications.
The consortium brings together groups from the University of Alcalá, the Severo Ochoa Molecular Biology Centre (CSIC-UAM), CEU San Pablo University, and the Health Research Institute of the Jiménez Díaz Foundation, along with patient associations. The project also aims to train young researchers to bring the advances into clinical practice.
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